Audiogenic kindling in Wistar and WAG/Rij rats: Kindling-prone and kindling-resistant subpopulations

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Play Fighting in Kindling-prone (fast) and Kindling-resistant (slow) Rats: Potential Genetic Controls over the Components of Play

Play fighting in kindling-prone (FAST) and kindling-resistant (SLOW) rats: Potential genetic controls over the components of play. Even though the behavioral components of play fighting have been well characterized in the rat, little is known about the underlying neurobehavioral mechanisms that control them. FAST and S L O W lines of selectively-bred rats were used to determine whether the comp...

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Inhibitory effects of succinic acid on chemical kindling and amygdala electrical kindling in rats.

AIM To investigate the effects and mechanism of succinic acid on pentylenetetrazol (PTZ) chemical kindling and amygdala electrical kindling in rats. METHODS PTZ chemical kindling and amygdala electrical kindling models were established in rats. The effects of succinic acid on the behavior and afterdischarge of kindled rats were observed. The mice were pretreated with succinic acid, 30 min lat...

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Kindling in alcohol withdrawal.

In many alcoholics, the severity of withdrawal symptoms increases after repeated withdrawal episodes. This exacerbation may be attributable to a kindling process. Kindling is a phenomenon in which a weak electrical or chemical stimulus, which initially causes no overt behavioral responses, results in the appearance of behavioral effects, such as seizures, when it is administered repeatedly. Bot...

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Frontal lobe and kindling in the rat.

To test the hypothesis that the cortex participates in amygdaloid kindling in rats, bilateral aspiration lesions were made in various cortical areas in rats prior to kindling. Lesions in orbital cortex (on the dorsal lip of the rhinal sulcus) or prefrontal cortex (area 10) significantly retarded the rate of amygdaloid kindling; lesions in motor cortex, anterior cingulate cortex, or visual corte...

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Hippocampal plasticity in the kindling model of epilepsy in rats.

Histochemical and autoradiographic techniques were used to study mossy fiber sprouting which occurs in the hippocampus of kindled rats. In rats kindled by daily stimulation of amygdala or entorhinal cortex, the mossy fibers sprout to innervate the supragranular zone of fascia dentata; this synaptic reorganization was associated with a significant increase in the density of high-affinity kainic ...

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ژورنال

عنوان ژورنال: Epilepsia

سال: 2008

ISSN: 0013-9580,1528-1167

DOI: 10.1111/j.1528-1167.2008.01617.x